Endogenous Estrogens, Estrogen Metabolites, and Breast Cancer Risk in Postmenopausal Chinese Women

Conclusions: Lower urinary parent estrogen concentrations and more extensive 2-hydroxylation were each associated with reduced postmenopausal breast cancer risk in a low-risk nation. Markedly higher total estrogen/estrogen metabolite concentrations in postmenopausal United States women (Asian Americans) than in Shanghai women may partly explain higher breast cancer rates in the United States.

Source: JNCI - May 17, 2016 Category: Cancer & Oncology Authors: Moore, S. C., Matthews, C. E., Ou Shu, X., Yu, K., Gail, M. H., Xu, X., Ji, B.-T., Chow, W.-H., Cai, Q., Li, H., Yang, G., Ruggieri, D., Boyd-Morin, J., Rothman, N., Hoover, R. N., Gao, Y.-T., Zheng, W., Ziegler, R. G. Tags: Article Source Type: research