Large-Effect Beneficial Synonymous Mutations Mediate Rapid and Parallel Adaptation in a Bacterium

This study shows that synonymous mutations can be fixed through strong positive selection, but the mechanism for their benefit varies depending on the local sequence context.

Source: Molecular Biology and Evolution - May 15, 2016 Category: Molecular Biology Authors: Agashe, D., Sane, M., Phalnikar, K., Diwan, G. D., Habibullah, A., Martinez-Gomez, N. C., Sahasrabuddhe, V., Polachek, W., Wang, J., Chubiz, L. M., Marx, C. J. Tags: Discoveries Source Type: research