Fibroblast growth factor 21 and exercise-induced hepatic mitochondrial adaptations

In conclusion, FGF21 does not appear necessary for exercise-induced systemic and hepatic mitochondrial adaptations, but the increased adiposity, hyperinsulinemia, and impairments in hepatic mitochondrial function induced by FGF21 deficiency can be partially rescued by daily wheel running exercise.

Source: AJP: Gastrointestinal and Liver Physiology - May 14, 2016 Category: Gastroenterology Authors: Fletcher, J. A., Linden, M. A., Sheldon, R. D., Meers, G. M., Morris, E. M., Butterfield, A., Perfield, J. W., Thyfault, J. P., Rector, R. S. Tags: LIVER AND BILIARY TRACT PHYSIOLOGY/PATHOPHYSIOLOGY Source Type: research