Mediastinal Gray Zone Lymphoma.

Mediastinal Gray Zone Lymphoma.
Indian J Chest Dis Allied Sci. 2015 Oct-Dec;57(4):255-7
Authors: Bhardwaj M, Saha R, Misra DS, Malhotra V
Abstract
A 50-year-old male presented with cough and breathlessness. A positron emissoin tomography scan revealed FDG (Fluorodeoxyglucose) avid mediastinal mass. Tru-cut biopsy showed fibrotic stromal tissue with cellular infiltrate consisting of abnormal lymphoid cells and few large cells with smudged nucleus. Immunohistochemistry revealed diffuse positivity with CD20, focal positivity for CD30 and rare CD15 positive cells. Histological picture and immune profile showed overlaping features of non-Hodgkin's as well as Hodgkin's lymphoma. A diagnosis of mediastinal gray zone lymphoma was made. The patient showed a complete metabolic response to six cycles of chemotherapy.
PMID: 27164737 [PubMed - in process]

Source: Indian Journal of Chest Diseases and Allied Sciences - May 14, 2016 Category: Respiratory Medicine Tags: Indian J Chest Dis Allied Sci Source Type: research