Relationship between High Frequency Oscillations and Spikes in a Case of Temporal Lobe Epilepsy

Conclusions These results agree that ripples are a marker for SOZ and co-occur with spikes. Seizure onset was heralded by an increase in ripples and spikes with ripples, without an increase in spikes without ripples. We hypothesize that spikes associated with ripples may have a somewhat different pathophysiological mechanism than spikes not associated with ripples, differences that may be relevant for the timing of seizure onset.

Source: Epilepsy and Behavior Case Reports - May 10, 2016 Category: Neurology Source Type: research