Prognosis and management of adult Wild Type GastroIntestinal Stromal Tumours (GISTs): A pooled analysis and review of literature

A pooled review was performed to determine survival in adult WT GIST (Wild Type GastroIntestinal Stromal Tumours) and compare the same with pediatric WT GISTs. Electronic databases were searched using the terms “Wild type” AND “GIST”. Eighty-two adult patients from 14 studies were included in the pooled analysis. Cumulative survival was greater than 50% in both age groups, hence medial survival could not be computed. Mean survival in adults was 15.7 years ± 0.78 and in children was 18.8 years ± 1.3 (p = 0.241).
Source: Surgical Oncology - Category: Surgery Authors: Source Type: research