Macitentan falls short to stop digital ulcers in systemic sclerosis

Macitentan failed to reduce digital ulcers in systemic sclerosis patients in a pair of randomized trials including approximately 500 adults. The findings were published online May 10 in JAMA. Digital ulcers occur in 35%-68% of systemic sclerosis patients, and endothelin-1 (ET-1) has demonstrated...
Source: Skin and Allergy News - Category: Dermatology Source Type: news