Importance of Donor Chondrocyte Viability for Osteochondral Allografts

Conclusion:
Viable chondrocytes in OCAs at the time of transplantation are primarily responsible for maintenance of donor articular cartilage health in the long term.

Clinical Relevance:
Optimizing chondrocyte viability in all aspects of OCA transplantation—including procurement, processing, storage, transportation, and surgical implantation—needs to be a primary focus for OCA clinical use.

Source: The American Journal of Sports Medicine - May 1, 2016 Category: Sports Medicine Authors: Cook, J. L., Stannard, J. P., Stoker, A. M., Bozynski, C. C., Kuroki, K., Cook, C. R., Pfeiffer, F. M. Tags: Biomechanics, articular cartilage, Cell/Molecular biology, Knee, articular cartilage, Allografts Source Type: research