Localizing Effects of Leptin on Upper Airway and Respiratory Control during Sleep

Conclusions:Leptin relieves upper airway obstruction in sleep apnea by activating the forebrain, possibly in the dorsomedial hypothalamus. In contrast, leptin upregulates ventilatory control through hindbrain sites of action, possibly in the nucleus of the solitary tract.Citation:Yao Q, Pho H, Kirkness J, Ladenheim EE, Bi S, Moran TH, Fuller DD, Schwartz AR, Polotsky VY. Localizing effects of leptin on upper airway and respiratory control during sleep. SLEEP 2016;39(5):1097–1106.
Source: Sleep - Category: Sleep Medicine Source Type: research