Guanosine and its modified derivatives are endogenous ligands for TLR7

In conclusion, our results provide evidence that G, dG, 8-OHG and 8-OHdG are novel endogenous ligands for TLR7.

Source: International Immunology - April 27, 2016 Category: Allergy & Immunology Authors: Shibata, T., Ohto, U., Nomura, S., Kibata, K., Motoi, Y., Zhang, Y., Murakami, Y., Fukui, R., Ishimoto, T., Sano, S., Ito, T., Shimizu, T., Miyake, K. Tags: featured content Source Type: research