Fructose-rich diet induces gender-specific changes in expression of the renin-angiotensin system in rat heart and upregulates the ACE/AT1R axis in the male rat aorta

Conclusions:
The FRD induced gender-specific changes in the expression of the RAS in the heart and aortae of male rats. Further investigations are required in order to get a comprehensive understanding of the underlying mechanisms of gender-specific fructose-induced cardiovascular pathologies.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - April 26, 2016 Category: Biomedical Science Authors: Bundalo, M. M., Zivkovic, M. D., Romic, S. D., Tepavcevic, S. N., Koricanac, G. B., Djuric, T. M., Stankovic, A. D. Tags: Original Article Source Type: research