Tumour immunology: Another string to the MYC bow
Nature Reviews Cancer 16, 273 (2016).
doi:10.1038/nrc.2016.47
Author: Gemma K. Alderton
Casey et al. show that MYC regulates the transcription of the immunoregulatory molecules CD47 and programmed cell death ligand 1 (PDL1). MYC bound to the promoters of CD47 and PDL1, and suppression of MYC resulted in reduced expression of CD47 and PDL1
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Gemma K. Alderton Tags: Research Highlight Source Type: research