Safety of Hydrophilic Guidewires used for Side-Branch Protection During Stenting and Proximal Optimization Technique in Coronary Bifurcation Lesions

Background and Propose.In coronary bifurcation lesions (CBL), hydrophilic guidewires used for side-branch (SB) protection can be withdrawn from underneath the stent easier than other wires. However, the safety of which has not been investigated.Methods/Materials.We performed scanning electron microscopic (SEM) examination of hydrophilic wires—the Whisper and Runthrough wires—used for SB protection during stenting and proximal optimization technique (POT) in 30 patients with CBL. The distal 15cm of the wire was examined every 1mm by SEM and 4500 segments were analyzed to investigate for wire fracture, polymer shearing (PS), and its correlations with post-stenting creatine kinase (CK)-MB release.

Source: Cardiovascular Revascularization Medicine - April 21, 2016 Category: Cardiology Authors: Arka Chatterjee, Brigitta C. Brott, Robin Foley, Oluseun Alli, Mark Sasse, Mustafa Ahmed, Firas Al Solaiman, Gautam Reddy, Sameer Ather, Massoud A. Leesar Source Type: research