Statistical Considerations for an Adaptive Design for a Serious Rare Disease

Conclusions:
The N-MOmentum study minimizes exposure to placebo for individual patients. The application of several statistical methods in the N-MOmentum trial is novel in NMOSD and aims to achieve a balance between minimizing risk and maintaining scientific integrity.

Source: Therapeutic Innovation and Regulatory Science - April 20, 2016 Category: Drugs & Pharmacology Authors: Patra, K., Cree, B. A. C., Katz, E., Pulkstenis, E., Dmitrienko, A., Cutter, G. Tags: Statistics Source Type: research