Development of immunization trials against Acinetobacter baumannii

Publication date: 2016 Source:Trials in Vaccinology, Volume 5 Author(s): Tarek A. Ahmad, Dina M. Tawfik, Salah A. Sheweita, Medhat Haroun, Laila H. El-Sayed Acinetobacter baumannii has recently crossed all lines once considered harmless, pushing its way as a nosocomial pathogen. It had acquired resistance to almost all available chemotherapies and mainly targets intensive care residents; causing pneumonia and major outbreaks with high mortality rates. This urged the need for preventive methods, which include infection control, non-specific immune-therapy, passive, and active immunization in order to offer vulnerable immune-compromised patients a flare in the dark. Several attempts were done for constructing effective vaccines with promising results. These are precisely classified, documented, and discussed in this up-to-date review.
Source: Trials in Vaccinology - Category: Infectious Diseases Source Type: research