Association of TIM‐1 5383‐5397ins/del and TIM‐3 ‐1541C>T polymorphisms with multiple sclerosis in Isfahan population

In this study, for the first time, the association of TIM‐1 5383‐5397ins/del and TIM‐3 ‐1541C>T polymorphisms with MS in an Iranian population was considered. The results of our study showed that there is no significant association between TIM‐1 5383‐5397ins/del and MS (P = 0.38); however, the frequency of CT genotype of TIM‐3 ‐1541C>T in patient group was significantly higher than the control group, and there was a significant association between CT genotype and MS (P = 0.009, OR = 4.08).
Source: International Journal of Immunogenetics - Category: Genetics & Stem Cells Authors: Tags: Original Article Source Type: research