Long Non-coding RNAs: an Emerging Powerhouse in the Battle between Life and Death of Tumor Cells
Long non-coding RNAs (lncRNAs) represent a class of non-protein coding transcripts longer than 200 nucleotides that have aptitude for regulating gene expression at the transcriptional, post-transcriptional or epigenetic levels. In recent years, lncRNAs, which are believed to be the largest transcript class in the transcriptomes, have emerged as important players in a variety of biological processes. Notably, the identification and characterization of numerous lncRNAs in the past decade has revealed a role for these molecules in the regulation of cancer cell survival and death.
Source: Drug Resistance Updates - Category: Drugs & Pharmacology Authors: Xing-dong Xiong, Xingcong Ren, Meng-yun Cai, Jay W Yang, Xinguang Liu, Jin-Ming Yang Source Type: research