Residual {beta}-Cell Function Predicts Clinical Response After Autologous Hematopoietic Stem Cell Transplantation
In conclusion, HOMA-IR and QUICKI could be optimal measurements for β-cell reserves, and they were predictive for the clinical response after auto-HSCT.
Significance
The β-score was comprehensive and reliable in evaluating clinical response after autologous hematopoietic stem cell transplantation (HSCT). The homeostasis model assessments for insulin resistance and the quantitative insulin sensitivity check index could serve as precise assessments for residual β-cell function and good predictors of clinical response. They might be used to select optimal clinical trial participants or predict the clinical response after auto-HSCT.
Source: Stem Cells Translational Medicine - Category: Stem Cells Authors: Xiang, H., Yang, C., Xiang, T., Wang, Z., Ge, X., Li, F., Su, Y., Chen, H., Huang, X., Zeng, Q. Tags: Mesenchymal Stem Cells, Standards, Policies, Protocols, and Regulations for Cell-Based Therapies Source Type: research
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