High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress

This study is the largest-scale high-throughput screen conducted using human astrocytes, with a total of 17,536 data points collected in the primary screen. The results demonstrate the relevancy and utility of using astrocytes differentiated from human stem cells as a disease model for drug discovery and development.

Source: Stem Cells Translational Medicine - April 17, 2016 Category: Stem Cells Authors: Thorne, N., Malik, N., Shah, S., Zhao, J., Class, B., Aguisanda, F., Southall, N., Xia, M., McKew, J. C., Rao, M., Zheng, W. Tags: Embryo Development, Cell-Based Drug Development, Screening, and Toxicology Source Type: research