Antifungal Drugs for Onychomycosis: Efficacy, Safety, and Mechanisms of Action.

Antifungal Drugs for Onychomycosis: Efficacy, Safety, and Mechanisms of Action. Semin Cutan Med Surg. 2016 Mar;35(3S):S51-S55 Authors: Rosen T, Stein Gold LF Abstract In 1996, oral terbinafine joined itraconazole and fluconazole on the short list of systemic medications that could be used to treat onychomycosis (although fluconazole was not approved for this indication by the US Food and Drug Administration [FDA], it was commonly used for this purpose). In 1999, ciclopirox was the first topical treatment to be FDA approved. The addition of the topical antifungal agents efinaconazole and tavaborole in 2014 expanded the roster of medications available to more effectively manage onychomycosis in a wide range of patients, including those for whom comorbid conditions, concomitant medications, or patient preference limited the use of systemic antifungals. Semin Cutan Med Surg 35(supp3):S51-S55. PMID: 27074700 [PubMed - as supplied by publisher]
Source: Seminars in Cutaneous Medicine and Surgery - Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research