A fundamental investigation into aspects of the physiology and biochemistry of the stratum corneum in subjects with sensitive skin

ConclusionsDespite the physiological similarities between the two groups of sensitive skin subjects, differences in their biochemistry were clearly evident. Lower levels of PCA, BH and TG activities together with a greater number of smaller and immature corneocytes indicate inferior SC maturation in the capsaicin‐sensitive subjects. The reduced maturation of corneocytes and thinner SC likely contributes to a greater penetration of capsaicin and the associated increased skin sensitivity.This article is protected by copyright. All rights reserved.

Source: International Journal of Cosmetic Science - March 31, 2016 Category: Dermatology Authors: N Raj, R Voegeli, A V Rawlings, S Doppler, D Imfeld, M R Munday, M E Lane Tags: Original Article Source Type: research