Pharmacologic Treatment Reduces Pressure Times Time Dose and Relative Duration of Intracranial Hypertension

Conclusion:
Baseline PTD values before drug administration reflects varied patient criticality, with much higher values seen before the use of mannitol or barbiturates. Treatment with HTS reduced PTD and PTI burden significantly more than escalation of sedation or pain management, and this effect remained significant at 2 hours after administration.

Source: Journal of Intensive Care Medicine - April 9, 2016 Category: Intensive Care Authors: Colton, K., Yang, S., Hu, P. F., Chen, H. H., Bonds, B., Stansbury, L. G., Scalea, T. M., Stein, D. M. Tags: Original Research Source Type: research