From Immune Substitution to Immunomodulation

Intravenous immunoglobulins (IVIG) are currently used in many fields of medicine for replacement and immunomodulation. This review focusses on the milestones in the history of human immunoglobulins since the initial observation by Ogden C. Bruton who described replacement therapy in a single boy with agammaglobulinemia. Since then, the preparations used for treatment have been markedly improved with respect to tolerability, clinical efficacy and pathogen safety. Preparations and appropriate pumps for s.c.

Source: Seminars in Hematology - April 6, 2016 Category: Hematology Authors: Volker Wahn Source Type: research