Beyond autophagy: New roles for ULK1 in immune signaling and interferon responses

ULK1 (Unc-51-like kinase 1) is a highly conserved serine/threonine kinase mainly known for its regulatory role in autophagy in response to nutrient deprivation [1,2]. However, recent findings have revealed a prospective role for ULK1 in regulation of innate immunity of interferons (IFNs) [3,4]. This opens a new field of investigation that could have important implications for the advancement of the IFN research field and change our overall understanding of the mechanisms behind IFN-mediated immune responses.
Source: Cytokine and Growth Factor Reviews - Category: Molecular Biology Authors: Tags: Mini review Source Type: research