Differential effects of hyaluronan synthase 3 deficiency after acute vs chronic liver injury in mice

Hyaluronan (HA) is a ubiquitous extracellular matrix (ECM) glycosaminoglycan synthesized by three different enzymes, hyaluronan synthase (HAS)1, 2, and 3. HA synthesis mediated by HAS3 promotes inflammation an...

Source: Fibrogenesis and Tissue Repair - March 31, 2016 Category: Biomedical Science Authors: Jennifer M. McCracken, Lu Jiang, Krutika T. Deshpande, Maura F. O’Neil and Michele T. Pritchard Source Type: research