Effects of quercetin, a natural phenolic compound, in the differentiation of human mesenchymal stem-cells (MSC) into adipocytes and osteoblasts

Natural phenols may have beneficial properties against oxidative stress, which is associated with aging and major chronic aging-related diseases, such as loss of bone mineral mass (osteoporosis) and diabetes. The main aim of this study was to analyze the effect of quercetin, a major nutraceutical compound present in the “Mediterranean diet”, on mesenchymal stem-cell (MSC) differentiation. Such cells were induced to differentiate into osteoblasts or adipocytes in the presence of two quercetin concentrations (0.1 and 10 μM).
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research