Public proteomics data: how the field has evolved from sceptical inquiry to the promise of in silico proteomics

Publication date: Available online 28 March 2016 Source:EuPA Open Proteomics Author(s): Lennart Martens Data sharing in the field of proteomics started from a rather negative perspective, with a focus on the validation of reported findings. Yet even from the very start, several repositories already focused on the much more positive aspect of data re-use, a strategy that is now pervasively adopted across all repositories and also ever more broadly applied in the field. While the enabling of results validation remains a core feature of data dissemination efforts, the much more positive focus on data re-use has combined synergistically with the availability of end-user oriented tools and services for data retrieval and re-analysis. As a result, the field today provides an unprecedented capacity for data re-use that is only held back somewhat by incomplete metadata reporting. Yet ever more user-friendly tools for data submission and increasing curatorial attention to annotation, together with strong interest in the calculation and provision of quality control metrics will almost certainly remove these last barriers towards achieving the full impact of what can rightfully be called in silico proteomics. Graphical abstract

Source: EuPA Open Proteomics - March 28, 2016 Category: Bioinformatics Source Type: research