Genetic polymorphism in postoperative sepsis after open heart surgery in infants

Conclusions Toll-like receptor 2 N199N polymorphism tends to increase the risk of sepsis (odds ratio = 1.974; 95% confidence interval: 0.23–16.92; p = 0.504), while toll-interacting protein rs5743867 polymorphism tends to decrease the risk of sepsis (odds ratio = 0.496; 95% confidence interval: 0.19–1.27; p = 0.139) in infants <1-year old undergoing complex open heart surgery.

http://aan.sagepub.com/cgi/content/abstract/24/4/326?rss=1

Source: Asian Cardiovascular and Thoracic Annals - March 27, 2016 Category: Cardiology Authors: Fakhri, D., Djauzi, S., Murni, T. W., Rachmat, J., Harahap, A. R., Rahayuningsih, S. E., Mansyur, M., Santoso, A. Tags: Cardiac Source Type: research