MMP-9-Dependent Serum-Borne Bioactivity Caused by Multiwalled Carbon Nanotube Exposure Induces Vascular Dysfunction via the CD36 Scavenger Receptor

In conclusion, pulmonary exposure to MWCNT leads to elevated MMP-9 levels and MMP-9-dependent generation of circulating bioactive factors that promote endothelial dysfunction and decreased NO bioavailability via interaction with vascular CD36.

Source: Toxicological Sciences - March 27, 2016 Category: Toxicology Authors: Aragon, M., Erdely, A., Bishop, L., Salmen, R., Weaver, J., Liu, J., Hall, P., Eye, T., Kodali, V., Zeidler-Erdely, P., Stafflinger, J. E., Ottens, A. K., Campen, M. J. Tags: Carbon Nanotube and Vascular Function Source Type: research