Molecular docking and binding study of harpagoside and harpagide as novel anti-inflammatory and anti-analgesic compound from Harpagophytum procumbens based on their interactions with COX-2 enzyme

Conclusions Results clearly revealed that harpagoside and harpagide act as potential highly selective COX-2 inhibitors. They are safe anti-inflammatory/analgesic compounds compared with classical non-steroidal anti-inflammatory drugs and could be considered as promising inflammatory inhibitors of a natural origin.
Source: Asian Pacific Journal of Tropical Disease - Category: Tropical Medicine Source Type: research