Influence of osteoclasts and osteoprotegerin on the mode of calcific degeneration of aortic valves.

CONCLUSIONS    The presence of osteoclasts in stenotic valves associated with low circulating OPG levels and an enhanced proportion of M2 macrophages can represent a variant of calcific aortic valve disease with a specifically regulated calcification process. PMID: 27003233 [PubMed - as supplied by publisher]
Source: Polskie Archiwum Medycyny Wewnetrznej - Category: Internal Medicine Tags: Pol Arch Med Wewn Source Type: research