Altered activity patterns of transcription factors induced by endoplasmic reticulum stress

The endoplasmic-reticulum (ER) responds to the burden of unfolded proteins in its lumen by activating intracellular signal transduction pathways, also known as the unfolded protein response (UPR). Many signal ...

Source: BMC Biochemistry - March 24, 2016 Category: Biochemistry Authors: Sheena Jiang, Eric Zhang, Rachel Zhang and Xianqiang Li Source Type: research