Length of optic nerve double inversion recovery hypersignal is associated with retinal axonal loss

Conclusions: Optic nerve DIR hypersignal length may be a biomarker for retinal axonal loss, easily applicable in routine and research on new anti-inflammatory or neuroprotective drug evaluation. Detection of subclinical ON with 3D-DIR in a non-negligible proportion of MS patients argues in favor of optic nerve imaging in future OCT MS studies, in order to achieve a better understanding of retinal axonal loss in non-ON eyes.

http://msj.sagepub.com/cgi/content/abstract/22/5/649?rss=1

Source: Multiple Sclerosis - March 23, 2016 Category: Neurology Authors: Hadhoum, N., Hodel, J., Defoort-Dhellemmes, S., Duhamel, A., Drumez, E., Zephir, H., Pruvo, J., Leclerc, X., Vermersch, P., Outteryck, O. Tags: Original Research Papers Source Type: research