Metastasis: The tumour microenvironment drives metastasis

Nature Reviews Cancer 16, 199 (2016). doi:10.1038/nrc.2016.31 Author: Gemma K. Alderton Mlecnik et al. analysed the genetics, levels of genomic instability, vascularization and the immunoscore (a measure of the 'immune contexture' of the tumour microenvironment) in a cohort of colorectal cancers. They found that FBXW7 mutations were inversely correlated with metastasis; genomic instability did
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research