Metastasis: The tumour microenvironment drives metastasis
Nature Reviews Cancer 16, 199 (2016).
doi:10.1038/nrc.2016.31
Author: Gemma K. Alderton
Mlecnik et al. analysed the genetics, levels of genomic instability, vascularization and the immunoscore (a measure of the 'immune contexture' of the tumour microenvironment) in a cohort of colorectal cancers. They found that FBXW7 mutations were inversely correlated with metastasis; genomic instability did
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Gemma K. Alderton Tags: Research Highlight Source Type: research