Nanosized Drug Delivery Systems for Direct Nose to Brain Targeting: A Review.

CONCLUSION: However, it is not yet confirmed whether the drug is freed from the formulation in the nasal cavity and then absorbed or the nanoparticles themselves are absorbed and then the drug is released in the CNS. Furthermore, the toxicity studies were not carried out extensively in suitably designed model, which should be considered before going for further studies and application. PMID: 26996366 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26996366?dopt=Abstract

Source: Recent Patents on Drug Delivery and Formulation - March 23, 2016 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research