A preliminary study of intranasal epinephrine administration as a potential route for anaphylaxis treatment

Conclusion: This preliminary study showed that epinephrine can be significantly absorbed via the IN route in humans. However, it requires a higher IN dose (5 mg) than the usual IM dose (0.3 mg) to achieve comparable systemic epinephrine absorption.humans. However, it requires a higher IN dose (5 mg) than the usual IM dose (0.3 mg) to achieve comparable systemic epinephrine absorption.
Source: Asian Pacific Journal of Allergy and Immunology - Category: Allergy & Immunology Source Type: research