Angioedema caused by ritonavir and risperidone

Many patients with HIV are likely to be prescribed antipsychotics, antidepressants, or anxiolytics to manage psychiatric symptoms. Some of the protease inhibitors used in the treatment of HIV are modulators of various metabolic enzymes, but limited information is available regarding the potential for drug interaction between protease inhibitors and psychotropic agents. The following report describes three cases of angioedema that could be related to a potential interaction between risperidone and ritonavir.
Source: The Brown University Psychopharmacology Update - Category: Psychiatry Authors: Tags: Drug ‐Drug Interactions Source Type: research