A case of ocular myasthenia: An eye-opener

We report a 32-year-male patient presenting with an acute onset total ophthalmoplegia. Ice-cooling test, edrophonium test and the repeated nerve stimulation test were found to be normal. A diagnosis of myasthenia gravis was made after a positive anti-acetylcholine receptor antibody test and treatment with pyridostigmine showed gradual improvement over 11 days. Isolated ocular myasthenia is a well-known entity but sudden onset complete ophthalmoplegia is rarely reported in literature. Our case not only puts forward the atypical presentation of myasthenia gravis but also is a reminder of the pitfalls of the conventional diagnostic modalities and states the triumph of early suspicion and rational treatment.
Source: Apollo Medicine - Category: Journals (General) Source Type: research