Impaired Angiogenic Potential of Human Placental Mesenchymal Stromal Cells in Intrauterine Growth Restriction

This study demonstrates that the loss of endothelial differentiation potential and the increase of adipogenic ability are likely to play a significant role in the vicious cycle of abnormal placental development in intrauterine growth restriction (IUGR). This is the first observation of a potential role for placental mesenchymal stromal cells in intrauterine growth restriction, thus leading to new perspectives for the treatment of IUGR.

Source: Stem Cells Translational Medicine - March 18, 2016 Category: Stem Cells Authors: Mando, C., Razini, P., Novielli, C., Anelli, G. M., Belicchi, M., Erratico, S., Banfi, S., Meregalli, M., Tavelli, A., Baccarin, M., Rolfo, A., Motta, S., Torrente, Y., Cetin, I. Tags: Tissue-Specific Progenitor and Stem Cells, Bridge Papers Source Type: research