Downregulation of Melanoma Cell Adhesion Molecule (MCAM/CD146) Accelerates Cellular Senescence in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells

This study provides strong evidence that CD146 is a novel and useful marker for predicting senescence in human umbilical cord blood-derived MSCs (hUCB-MSCs), and CD146 can potentially be applied in quality-control assessments of hUCB-MSC-based therapy.

Source: Stem Cells Translational Medicine - March 18, 2016 Category: Stem Cells Authors: Jin, H. J., Kwon, J. H., Kim, M., Bae, Y. K., Choi, S. J., Oh, W., Yang, Y. S., Jeon, H. B. Tags: Fetal and Neonatal Stem Cells, Cord Blood Stem Cells Source Type: research