The impact of theaflavins on systemic-and microcirculation alterations: the murine and randomized feasibility trials

Theaflavins are polyphenols found in black tea, their physiological activities were not well investigated. The present study in rats evaluated the influence of theaflavins on circulation. In addition, an intervention pilot study examined the influence of a theaflavin drink on postprandial hemodynamic change. In animal study, a single oral dose of theaflavin rich fraction (TF, 10mg/kg) caused transient increase in mean blood pressure (MBP) and heart rate (HR). TF also elevated cremastric blood flow significantly and the magnitude of this effect was as following order: theaflavin 3’-O-gallate (TF2B) >> theaflavin-3-O-gallate (TF2A) > >theaflavin (TF1) = theaflavin-3, 3’-di-O-gallate (TF3).
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research