Bisphenol A Concentrates Preferentially in Human Uterine Leiomyoma and Induces Proliferation in Rat Myometrium

Conclusion:
Bisphenol A concentrates in human ULM tissue and its adjacent Myo-F compared to Myo-N. No significant difference is detected in BPA content of ULM tissue of different subtypes. Bisphenol A increases thickness and induces cellular proliferation in rat myometrium. Taken together, our results support a role of BPA in ULM development/growth.

Source: Reproductive Sciences - March 18, 2016 Category: Reproduction Medicine Authors: Othman, E. R., Al-Adly, D. M. M., Elgamal, D. A., Ghandour, N., El-Sharkawy, S. Tags: Original Articles Source Type: research