Targeted Adenoviral Vector Demonstrates Enhanced Efficacy for In Vivo Gene Therapy of Uterine Leiomyoma

Conclusion:
Targeted adenovirus, effectively reduces tumor size in leiomyoma without dissemination to other organs. Further evaluation of this localized targeted strategy for gene therapy is needed in appropriate preclinical humanoid animal models in preparation for a future pilot human trial.

Source: Reproductive Sciences - March 18, 2016 Category: Reproduction Medicine Authors: Abdelaziz, M., Sherif, L., ElKhiary, M., Nair, S., Shalaby, S., Mohamed, S., Eziba, N., El-Lakany, M., Curiel, D., Ismail, N., Diamond, M. P., Al-Hendy, A. Tags: Original Articles Source Type: research