Effects of the Oral Oxytocin Receptor Antagonist Tocolytic OBE001 on Reproduction in Rats

Conclusion:
OBE001 at up to 125 mg/kg/d had no effects on EED and no adverse effects on FD and postnatal development of rats. These results constitute an important step toward the development of OBE001 in preterm labor and ART indications.

Source: Reproductive Sciences - March 18, 2016 Category: Reproduction Medicine Authors: Pohl, O., Perks, D., Rhodes, J., Comotto, L., Baldrick, P., Chollet, A. Tags: Original Articles Source Type: research