Cytokeratin 5/6 and P63 immunophenotype of thyroid lymphoepithelial complexes

Thyroid lymphoepithelial complexes (LECos) are rare, being reported in lymphoma, Graves-Basedow disease, Hashimoto thyroiditis, pericarcinomatous thyroid or in the context of branchial cleft-like cysts.Here we report immunohistochemical expression of cytokeratin 5/6, P63 and TTF1 in 6 cases of thyroid LECos.Two cases had carbimazole treatment for hyperthyroidia and Graves disease. Anti-thyroglobulin,-thyroperoxidase or -TSH antibodies were detected in 4 cases. NSAID or poviodone iodine allergy were present in 2 cases.
Source: Annals of Diagnostic Pathology - Category: Pathology Authors: Source Type: research