Influences of dietary vitamin D restriction on bone strength, body composition, and muscle in rats fed a high-fat diet: Involvement of mRNA expression of MyoD in skeletal muscle

Vitamin D insufficiency is associated with a greater risk of osteoporosis and also influences skeletal muscle functions, differentiation, and development. The present study investigated the influences of vitamin D restriction on the body composition, bone, and skeletal muscle in rats fed a high-fat diet. Sprague–Dawley strain male rats (11 weeks old) were divided into four groups and fed experimental diets: a basic control diet (Cont.), a basic control diet with vitamin D restriction (DR), a high-fat diet (F), and a high-fat diet with vitamin D restriction (FDR).

Source: The Journal of Nutritional Biochemistry - March 11, 2016 Category: Biochemistry Authors: Yuno Oku, Rieko Tanabe, Kanae Nakaoka, Asako Yamada, Seiko Noda, Ayumi Hoshino, Mayu Haraikawa, Masae Goseki-Sone Source Type: research