Glucose metabolism during fasting is altered in experimental porphobilinogen deaminase deficiency

In conclusion, AIP mice showed a different response to fasting as measured by altered carbohydrate metabolism in the liver and modified glucose consumption in the brain cortex. Glucose homeostasis in fasted AIP mice was efficiently normalized after restoration of PBGD gene expression in the liver.

Source: Human Molecular Genetics - March 11, 2016 Category: Genetics & Stem Cells Authors: Collantes, M., Serrano-Mendioroz, I., Benito, M., Molinet-Dronda, F., Delgado, M., Vinaixa, M., Sampedro, A., Enriquez de Salamanca, R., Prieto, E., Pozo, M. A., Penuelas, I., Corrales, F. J., Barajas, M., Fontanellas, A. Tags: ARTICLES Source Type: research