Long-term insulin treatment restores cardioprotection induced by sufentanil postconditioning in diabetic rat heart

In conclusion, sufentanil-induced cardioprotection was restored by long-term insulin treatment. The underlying mechanism may be increased phosphorylation of glycogen synthase kinase-3β.

Source: Experimental Biology and Medicine - March 8, 2016 Category: Research Authors: Zhang, Y., Zhang, L., Gu, E., Zhu, B., Zhao, X., Chen, J. Tags: Pharmacology/Toxicology Source Type: research