Combination therapy in hypertension: From effect on arterial stiffness and central haemodynamics to cardiovascular benefits

Measures of arterial aging have the potential to improve risk prediction beyond traditional risk scores. Such biomarkers that fulfil most, or some of the strict criteria of a surrogate end-point are aortic stiffness (IIa level of recommendation in European Guidelines and Position Papers) and central haemodynamics (IIb level of recommendation). Early intervention towards improving aortic elastic properties acquires particular importance since evidence suggests that arterial stiffening may occur before the onset of hypertension.
Source: Artery Research - Category: Cardiology Authors: Tags: Review Source Type: research