Single-dose dexamethasone for the prevention of pemetrexed associated cutaneous adverse reactions
We report 14 cases of metastatic non-small-cell-lung-cancer patients who were premedicated with a single dose of dexamethasone 20 mg prior to pemetrexed or pemetrexed-based chemotherapy. None of these patients reported a grade 3 or above skin reactions over the course of their treatments. These findings suggest that a single dose of dexamethasone 20 mg may be an alternative premedication regimen in patients with metastatic non small cell lung cancer receiving pemetrexed or pemetrexed-based chemotherapy.
Source: Journal of Oncology Pharmacy Practice - Category: Cancer & Oncology Authors: Elsoueidi, R., Lander, M. J., Richa, E. M., Adane, E. D. Tags: Original Articles Source Type: research
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